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    Essays on the Network Analysis of Culture

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    Nelle relazioni economiche, negli accordi internazionali e nel dialogo istituzionale, la parola distanza \ue8 una delle pi\uf9 enunciate. Ci sono distanze esogene da colmare per creare legami, a volte ci sono chiusure necessarie e altre volte rotture inevitabili, ma questo pu\uf2 dipendere, cos\uec come le distanze geografiche e fisiche, e gli interessi impliciti, in gran parte dallo status culturale di gruppi di individui. La valutazione quantitativa della distanza tra due entit\ue0 \ue8 una propriet\ue0 diadica ed in quanto tale, la presenza, intensit\ue0, direzione e segno di un legame rappresenta un modo per catturarla. Poich\ue9 le entit\ue0 possono essere individui, oggetti, societ\ue0, paesi, pianeti, cos\uec come reti che si riferiscono a contesti specifici, e il modo di misurare la somiglianza tra di loro pu\uf2 essere vario, una cosa peculiare delle distanze \ue8 la loro natura mutevole. Mentre le distanze fisiche sono quasi oggettivamente calcolabili, nel caso della cultura (ed anche di altri concetti pi\uf9 o meno ampi) l\u2019utilizzo di un metodo rispetto ad un altro potrebbe cambiare radicalmente la relazione di distanza tra le entit\ue0, soprattutto se esse hanno un alto grado di complessit\ue0. Il bagaglio culturale svolge un ruolo importante nel determinare lo status socio-economico di un paese e la sua caratterizzazione in termini di somiglianza con altri paesi. Il Capitolo 1 - utilizzando i dati della WVS/EVS Joint 2017 - operativizza una definizione di cultura che tiene conto delle interdipendenze tra tratti culturali a livello di paese e propone una nuova misura di distanza culturale. Sfruttando un recente algoritmo Bayesiano di Copula Gaussian graphical models, questo Capitolo stima per ciascuno di 76 paesi inclusi nella WVS/EVS Joint 2017, la rete culturale di interdipendenze tra tratti culturali considerando diversi insiemi di essi: i 6 della prima batteria di domande, i 10 della mappa culturale di Inglehart-Welzel, i 14 della mappa culturale di Inglehart-Welzel, dove per gli indici di \u201cPost-materialism\u201d e \u201cAutonomy\u201d sono state utilizzate le variabili da cui sono ricavate, e 60 tratti culturali dei quali, 14 come definiti in precedenza, 6 fanno riferimento alla prima batteria di domande e i restanti 40 sono selezionati in modo da ottenere un numero di variabili che possa far fronte al trade-off tra il tempo di elaborazione dell\u2019algoritmo e il minimo numero di valori mancanti per paese. Dopo aver definito le distanze tra i paesi considerando sia le reti culturali che le distribuzioni dei tratti culturali, attraverso il metodo DISTATIS, questo Capitolo osserva come l'aggiunta della componente di rete a quella distributiva classica, modifichi sostanzialmente la misura della distanza culturale sia nel caso di pochi tratti culturali (6, 10 e 14) che nel caso di pi\uf9 tratti culturali (60). Infine, esso afferma che la struttura di rete della cultura nazionale \ue8 importante per la definizione della distanza culturale tra i paesi del mondo e trova due misure finali di distanza: il Compromise_Large (da 60 variabili) e il Compromise_IW (dalle variabili della mappa culturale di Inglehart-Welzel). L'effetto delle variabili culturali sulla situazione economica di un paese, o pi\uf9 in generale di un'area geograficamente definita, \ue8 stato negli ultimi anni scandagliato dalla letteratura economica. Le distanze culturali, genetiche, geografiche, climatiche, semantiche, etniche, linguistiche, politiche sono state spesso incluse nei modelli econometrici come variabili indipendenti o di controllo. Il Capitolo 2 segue questa letteratura, prima confrontando individualmente tre misurazioni della distanza culturale calcolate nel Capitolo 1 con altre distanze usate in letteratura assieme alla distanza culturale o come proxy di essa, e poi confrontandole (le misure di distanza culturale e quelle dalla letteratura) congiuntamente tramite DISTATIS. Le tre distanze culturali sono le due nuove misure di cui sopra (Compromise_Large e Compromise_IW) e l'IW index ottenuto come distanza euclidea tra i paesi nella mappa culturale di Inglehart-Welzel, mentre le altre distanze prendono in considerazione la condizione climatica, l'etnia e la lingua, la genetica ed il recente fenomeno di Facebook. Infine, questo Capitolo considera tutte le misure di distanza all\u2019interno di un Social Relations Regression Model (SRRM) che stima la distanza tra i paesi in base al PIL pro capite (anno 2017). Il risultato finale mostra che le distanze culturali sono poco correlate con le distanze prese dalla letteratura, e quando si trova un compromesso tra di loro, di solito la Compromise_Large \ue8 caratterizzata da un peso leggermente superiore. La conclusione principale riguarda l'importante potere esplicativo della distanza Compromise_Large sulla distanza in PIL pro capite rispetto a quello della IW index e della Compromise_IW, la quale ha un significato intermedio tra le due. Ci\uf2 conferma l'importanza di considerare la rete culturale nazionale di interdipendenze tra tratti culturali nella definizione generale della distanza culturale, ed anche che l\u2019aggiunta di un numero maggiore di tratti culturali pu\uf2 influire nella sua specificazione, seppur i tratti culturali considerati da Ronald Inglehart e Christian Welzel nella costruzione della loro mappa culturale sembrano catturare gi\ue0 una buona parte dell\u2019informazione culturale dei paesi. La produzione abnorme di dati nel nostro tempo ha permesso l'osservazione di grandi collezioni di reti all\u2019interno di un campo di analisi specifico, le quali possono essere caratterizzate anche da una diversa dimensione l\u2019una dall\u2019altra (ad esempio si pu\uf2 pensare alla rete commerciale tra paesi di ogni prodotto). Una rete \ue8 un oggetto complesso, per cui un modo comune per analizzare e comparare congiuntamente un set di reti \ue8 ridurne la complessit\ue0 proiettandole in uno spazio ridotto attraverso i descrittori che le caratterizzano. \uc8 qui che sorge il problema analizzato nel Capitolo 3: qual \ue8 il sottoinsieme di descrittori che mantiene le caratteristiche delle reti il pi\uf9 possibile invariate nel processo di mapping, ovvero proietta in punti diversi dello spazio reti non isomorfe e raggruppa vicine reti strutturalmente simili tra di loro e lontano reti dissimili? Attraverso una simulazione di reti da quattro modelli generativi (Random, Scale-free, Small-world e Stochastic block model) e la selezione di un ampio insieme di descrittori riferenti ai livelli micro, meso e macro di analisi della rete, questo Capitolo trova tramite il metodo di Subgroup Discovery un piccolo sottoinsieme di descrittori. Questo sottoinsieme \ue8 composto da 5 descrittori: il momento primo del Coefficiente di Clustering Locale, 3 configurazioni di Motifs e il descrittore di Smallworldness. L'efficacia dei descrittori \ue8 valutata applicandoli all'insieme delle reti culturali binarie con 60 tratti culturali stimate nel Capitolo 1 e confrontando le distanze tra questi punti-rete nello spazio dei descrittori con distanze di reti popolari in letteratura. Le principali innovazioni sono due: la costruzione di un nuovo indice di distanza culturale tra i paesi, in cui \ue8 inclusa la rete culturale di interdipendenze tra tratti culturali; la selezione di un piccolo sottoinsieme efficiente di descrittori per la proiezione nello spazio di insiemi di reti binarie che possono avere grandezza diversa l\u2019una dall\u2019altra.In economic relations, in international agreements and in institutional dialogue, the word distance is one of the most enunciated. There are exogenous distances to be bridged to ignite a bond, sometimes there are necessary cracks and other times unavoidable breaks, but this may depend, as well as geographical and physical distances, and implicit interests, largely on the cultural status of groups of individuals. The quantitative evaluation of the distance between two entities is a dyadic property and as such, the presence, intensity, direction and sign of their tie is a way to undertake it. Since entities can be individuals, objects, companies, countries, planets, as well as networks referring to specific contexts, and the way to measure similarity between them is various, a peculiarity thing of distances is their changeable nature. While physical distances are almost objectively computable, in case of culture (and even other more or less broad concepts) using a method rather than another could radically change the proximity relationship between entities, especially if they have a high degree of complexity. The cultural background plays an important role in determining the socio-economic status of a country and its characterization in terms of similarity to other countries. The Chapter 1 - using data from the WVS/EVS Joint 2017 - operationalizes a definition of culture that takes into account the interdependencies between cultural traits at country level and calculates a new measure of cultural distance. Taking advantage of a recent Bayesian algorithm by Gaussian copula graphical model, this Chapter estimates for each of 76 countries included in the WVS/EVS Joint 2017, the cultural network of interdependencies between cultural traits considering different sets of them: the 6 from the first battery of questions, the 10 of the Inglehart-Welzel Cultural Map, the 14 of the Inglehart-Welzel Cultural Map, where for \u201cPost-materialism\u201d and \u201cAutonomy\u201d indices are used the variables from which they are derived, and 60 cultural traits of which, 14 as previously defined, 6 refer to the first battery of questions and the remaining 40 are selected to get a number that can cope with the trade-off between processing time and the minimum number of missing values per country. After defining the distances between countries considering both cultural networks and distributions of cultural traits, this Chapter observes via DISTATIS how the addition of the network component to the classic distributional one, substantially modifies the measure of cultural distance both in the case of a few cultural traits (6, 10 and 14) and in the case of more cultural traits (60). Finally, it affirms that the network structure of the national culture matters for the definition of the cultural distance among worldwide countries and finds two final distance measures: Compromise_Large (from 60 variables) and Compromise_IW (from the Inglehart-Welzel cultural map variables). The effect of cultural variables on the economic situation of a country or more generally of a geographically definable area, has been scoured in recent years by the economic literature. Cultural, genetic, geographical, climatic, semantic, ethnic, linguistic, political distances have often been included in econometric models as independent or control variables. The Chapter 2 follows this literature, firstly by individually comparing three measurements of cultural distance calculated in Chapter 1 with other distances used in literature together with cultural distance or as a proxy of it, and secondly by jointly comparing them (the measurements of cultural distance and those from literature) via DISTATIS. The three cultural distances are the two new measures mentioned above (Compromise_Large and Compromise_IW) and the IW index obtained as Euclidean distance between countries in the Inglehart-Welzel cultural map, while the other distances take into consideration climatic condition, ethnicity and language, genetics and the recent phenomenon of Facebook. Finally, this Chapter considers these distance measures into a Social Relations Regression Model (SRRM) which estimates the distance between countries in GDP per capita (year 2017). The final result shows that cultural distances are poorly correlated with the distances from the literature, and when a compromise is found between them, usually the Compromise_Large is characterized by a slightly higher weight. The main conclusion concerns the important explanatory power of the Compromise_Large distance on the distance in GDP per capita compared to that of the IW index and the Compromise_IW, which has an intermediate meaning between the two. This confirms the importance of considering the national cultural network of interdependencies between cultural traits in the overall definition of cultural distance, and also that the addition of more cultural traits may influence its specification, although the cultural traits considered by Inglehart and Welzel in the construction of their cultural map seem to capture already a good part of the cultural information of the countries. The abnormal production of data in our time has allowed the observation of large collections of networks within a specific field of analysis, which can also be characterized by a different size from each other, e.g. you can think of the trade network of each product between countries. A network is a complex object, so a common way to analyze and compare a set of networks is to reduce their complexity by mapping them into a space through the descriptors that characterize them. This is where the problem analyzed in Chapter 3 arises: what is the subset of descriptors that keeps the characteristics of networks as much as possible unchanged in the mapping process, namely projects non-isomorphic networks in different points of the space and groups nearby networks structurally similar and distant networks dissimilar? Through a simulation of networks from four generative models (Random, Scale-free, Small-world and Stochastic block model) and the selection of a wide set of descriptors of the micro, meso and macro-level of network analysis, this Chapter finds evidence of a small subset of descriptors via Subgroup Discovery. This subset is composed by 5 descriptors: the first moment of the Local Clustering Coefficient, 3 Motifs configurations and the descriptor of Smallworldness. The effectiveness of descriptors is evaluated by applying them to the set of binary cultural networks with 60 cultural traits estimated in Chapter 1 and comparing distances between these points-network in the space of the descriptors with popular network distances used in literature. Two are the main innovations: the construction of a new index of cultural distance among countries, in which is included the cultural network of interdependencies among cultural traits; the selection of a small efficient subset of descriptors for mapping in the space of sets of binary networks, which can also be characterized by a different size from each other

    The network structure of cultural distances

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    This paper proposes a novel measure of cultural distances between countries. Making use of the information coming from the World Value Survey (Wave 6), and considering the interdependence among cultural traits, the paper proposes a methodology to define the cultural distance between countries, that takes into account the network structure of national cultural traits. Exploiting the possibilities offered by Copula graphical models for ordinal and categorical data, the paper infers the network structure of 54 countries and proposes a new summary measure of national cultural distances. The DBRV Cultural Distance index shows that, as for 2010-2014, compared to Inglehart and Welzel (2005) the world appears to be more culturally heterogeneous than what it was previously thought.Comment: 64 pages, 67 figures, 4 table

    The protective effect of the Mediterranean diet on endothelial resistance to GLP-1 in type 2 diabetes: a preliminary report

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    In type 2 diabetes, acute hyperglycemia worsens endothelial function and inflammation,while resistance to GLP-1 action occurs. All these phenomena seem to be related to the generation of oxidative stress. A Mediterranean diet, supplemented with olive oil, increases plasma antioxidant capacity, suggesting that its implementation can have a favorable effect on the aforementioned phenomena. In the present study, we test the hypothesis that a Mediterranean diet using olive oil can counteract the effects of acute hyperglycemia and can improve the resistance of the endothelium to GLP-1 action

    Prioritizing high-contact professions raises effectiveness of vaccination campaigns

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    Recent studies have proposed network interventions for reducing the propagation of COVID-19. By restricting close range contact to occur only within predetermined interaction structures, the speed and reach of COVID-19 spread can theoretically be reduced. However, even severe social distancing policies such as full-scale lockdowns can only temporarily reduce infections and hospitalizations, leaving large-scale vaccination as the primary vehicle for sustainable control over the SARS-CoV-2 virus. Nonetheless, global vaccine roll-out has logistical and financial limits. The challenge is how to effectively control the virus with limited supplies. A twenty-year-old idea from network science is that vaccination campaigns would be much more effective if high contact individuals were preferentially targeted. Implementation is impeded by the ethical and practical problem of differentiating vaccine access on the basis of a personal characteristic that is informal and private. Here we develop an agent-based model on how to effectively vaccinate in times of a pandemic by prioritizing specific occupational groups. We draw on data from a survey conducted at the beginning of the COVID-19 pandemic in early 2020 that measures close-range contact for occupational groups. The data reveal substantial occupational differences, with teachers and cashiers being among the most connected and computer programmers among the least connected. To investigate whether this variability can produce significant gains when exploited in targeted vaccination programs, we first used a genetic algorithm to generate networks of 10,000 nodes that map the occupational contact data onto network degree. We then simulated epidemics and compared the effectivity of vaccination campaigns that target individuals either randomly or targeted by occupational group membership, prioritizing the highest reported average number of social contacts. Our simulations suggest that random distribution of vaccines amounts to 35% of nodes getting infected on average, compared to 60% in the baseline/no-vaccination condition. Prioritizing high contact professions, however, results in a mean of 20% of nodes getting infected, while the vast majority of epidemics are prevented entirely (median number of infections close to 0%). Furthermore, we show that the positive effect of targeted vaccination is stronger if networks are more clustered and if there is lower occupational group homophily. A comparison between random vaccination of 40% and targeted vaccination of 20% of the population (everything else equal) shows that the latter achieves similar numbers of cumulative infections with significantly later and lower epidemic peaks. Based on our findings, we propose that occupational groups can function as a reasonably effective proxy to increase effectiveness of vaccination campaigns

    Benthic estuarine communities in Brazil: moving forward to long term studies to assess climate change impacts

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    The complete genome sequence of Chromobacterium violaceum reveals remarkable and exploitable bacterial adaptability

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    Chromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spread utilization of quorum sensing for control of inducible systems, all of which underpin the versatility and adaptability of the organism. The genome also contains extensive but incomplete arrays of ORFs coding for proteins associated with mammalian pathogenicity, possibly involved in the occasional but often fatal cases of human C. violaceum infection. There is, in addition, a series of previously unknown but important enzymes and secondary metabolites including paraquat-inducible proteins, drug and heavy-metal-resistance proteins, multiple chitinases, and proteins for the detoxification of xenobiotics that may have biotechnological applications
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